Orphan G Protein-Coupled Receptors and Novel Neuropeptides ILO ) from the year 2014

) from the year 2014 in the subject Chemistry - Bio-chemistry

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Orphan G Protein-Coupled Receptors and Novel Neuropeptides ILO ) from the year 2014Over the last decade it has been shown that orphan G protein coupled receptors (GPCRs) can be used as targets to discover novel neuropeptides. A dozen neuropeptides have been identified through this approach. Each of these neuropeptides has opened new doors for our understanding of fundamental physiological or behavioral responses. For example the orexins, MCH and ghrelin carry fundamental roles in regulating food intake while neuropeptide S,